Tablet Presentation

Each Tablet Contains:
Thyroxine Sodium IP 12.5/25/50/75/100/125 MCG

Thyroxine is a medicine used to treat an underactive thyroid gland (hypothyroidism). The thyroid gland makes thyroid hormone which helps to control energy levels and growth. Thyroxine is taken to replace the missing thyroid hormone.

Indications

Thyroxine oral tablet is used to treat hypothyroidism. It’s also used to treat goiter and certain types of thyroid cancer.

Pharmacology

1. Thyroid hormones effect the metabolism of lipid, carbohydrates, protein. they enhance lipolysis and the utilization of the sugars by tissues is also increased, faster absorption of glucose from the intestine is also increased i.e. hyperglycemia, proteins synthesis is also increased; prolonged use can cause negative nitrogen balance and muscle wasting
2. It also fastens the heart rate, contraction and increases cardiac output
3. It can cause cretinism, sluggishness
4. Muscles becomes weak
5. Peristalsis movement is increased in the GIT and may cause diarrhea too in some patients
6. In kidney – the flow of urine is increased
7. Anemia is developed in hypothyroid patients
8. In hypothyroidism, women are suffering from oligomenorrhoea

Mechanism of Action

Thyroxine works by providing the thyroid hormone that your thyroid gland would produce if it were working normally.

Pharmacokinetics

It is absorbed orally but its absorption decreases with food
Oral bioavailability of thyroxine is 75%

Side Effects

• Increased appetite
• Weight variations
• Headache
• Vomiting
• Diarrhoea
• Cramps

Contraindication

• If you are allergic to Levothyroxine or any ingredient of Thyronorm.
• If you have any disorder related to adrenal glands.
• If you have a condition Thyrotoxicosis (excess of thyroid hormone in the bloodstream).

Storage

Store it at room temperature.

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